A lysosome-specific two-photon phosphorescent binuclear cyclometalated platinum(ii) probe for in vivo imaging of live neurons
Chemical Communications2014Vol. 50(32), pp. 4161–4161
Citations Over TimeTop 12% of 2014 papers
Yu‐Man Ho, Ngan Pan Bennett Au, Ka‐Leung Wong, Chris Tsz‐Leung Chan, Wai‐Ming Kwok, Ga‐Lai Law, Kwong-Kit Tang, Wai‐Yeung Wong, Chi Him Eddie, Michael Hon‐Wah Lam
Abstract
Real-time tracking of fast axonal transport of acidic vesicles in live adult mouse dorsal root ganglion (DRG) and cortical neurons in brain slices was visualized by the use of binuclear cycloplatinated complexes, {[Pt(L1)]2(μ-dppm)}(2+) (1) and {[Pt(L2)]2(μ-dppm)}(2+) (2), as lysosome-specific two-photon imaging probes.
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