Linker-determined drug release mechanism of free camptothecin from self-assembling drug amphiphiles
Chemical Communications2014Vol. 50(45), pp. 6039–6042
Citations Over TimeTop 10% of 2014 papers
Abstract
We report here that the release mechanism of free camptothecin from self-assembling drug amphiphiles can be regulated by use of different linker groups. Our results highlight the significance of the linker group of drug amphiphiles on the drug release efficiency and their consequent in vitro efficacy.
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