Manganese(iii)-mediated direct Csp2–H radical trifluoromethylation of coumarins with sodium trifluoromethanesulfinate
Chemical Communications2014Vol. 50(25), pp. 3359–3359
Citations Over TimeTop 10% of 2014 papers
Abstract
Mn(OAc)3-mediated direct Csp2-H radical trifluoromethylation of coumarins with CF3SO2Na (Langlois reagent) to afford selective 3-trifluoromethyl coumarins in moderate to good yields is described. This methodology can also be applied to the trifluoromethylation of quinolinones and pyrimidinones.
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