Novel porphyrin–psoralen conjugates: synthesis, DNA interaction and cytotoxicity studies
Organic & Biomolecular Chemistry2013Vol. 11(39), pp. 6675–6675
Citations Over TimeTop 16% of 2013 papers
Dalip Kumar, Bhupendra Mishra, K. P. Chandra Shekar, Anil Kumar, Kanako Akamatsu, Ryohsuke Kurihara, Takeo Itô
Abstract
A Cu(i)-catalyzed azide-alkyne cycloaddition reaction (CuAAC) has been utilized to prepare novel triazole-linked cationic porphyrin-psoralen conjugates that exhibited significant photocytotoxicity against A549 cancer cells (IC50 = 84 nM).
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