Rational design of biotinylated probes: fluorescent turn-on detection of (strept)avidin and bioimaging in cancer cells
Chemical Communications2014Vol. 50(62), pp. 8518–8518
Citations Over TimeTop 10% of 2014 papers
Abstract
Two fluorescent probes SPS1 and SPS2 were designed by connecting biotin to an environment-sensitive coumarin fluorophore. Streptavidin and avidin induced dramatical fluorescence changes in both probes. SPS2 has potential in fluorescent imaging of biotin receptor-enriched tumor cells.
Related Papers
- → Switchavidin: Reversible Biotin–Avidin–Biotin Bridges with High Affinity and Specificity(2014)36 cited
- → A comparison of the binding of biotin and biotinylated macromolecular ligands to an anti-biotin monoclonal antibody and to streptavidin(1993)25 cited
- → Methods to determine biotin-binding capacity of streptavidin-coated magnetic particles(1999)21 cited
- → Cellular Uptake of Fluorescent Labelled Biotin–Streptavidin Microspheres(2008)16 cited
- → Oligonucleotide-Blocked Streptavidin for Biotinylation Analysis(2022)2 cited