An efficient regioselective hydrodifluoromethylation of unactivated alkenes with TMSCF2CO2Et at ambient temperature
Chemical Communications2014Vol. 50(68), pp. 9749–9752
Citations Over TimeTop 10% of 2014 papers
Abstract
A mild, versatile and efficient method for the regioselective hydrodifluoromethylation of unactivated alkenes has been developed. This Ag-mediated Csp(3)-CF2 bond forming reaction provides easy access to a variety of vicinal α-difluoroacetate-containing alkanes.
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