Cascade catalysis – strategies and challenges en route to preparative synthetic biology
Chemical Communications2014Vol. 51(27), pp. 5798–5811
Citations Over TimeTop 1% of 2014 papers
Jan Muschiol, Christin Peters, Nikolin Oberleitner, Marko D. Mihovilovič, Uwe T. Bornscheuer, Florian Rudroff
Abstract
Nature's smartness and efficient assembling cascade type reactions inspired biologists and chemists all around the world. Tremendous effort has been directed towards the understanding and mimicking of such networks. In recent years considerable progress has been made in developing multistep one-pot reactions combining either advantage of chemo-, regio-, and stereoselectivity of biocatalysts or promiscuity and productivity of chemocatalysts. In this context several concepts, inspired by different disciplines (biocatalysis, metabolic engineering, synthetic chemistry, and material science), have been evolved. This review will focus on major contributions in the field of cascade reactions over the last three years.
Related Papers
- → Recent applications of synthetic biology tools for yeast metabolic engineering(2014)107 cited
- → Rational construction of synthetic consortia: Key considerations and model-based methods for guiding the development of a novel biosynthesis platform(2024)19 cited
- → Review of Microfluidic Photobioreactor Technology for Metabolic Engineering and Synthetic Biology of Cyanobacteria and Microalgae(2016)22 cited
- → METABOLIC MODELLING IN THE DEVELOPMENT OF CELL FACTORIES BY SYNTHETIC BIOLOGY(2012)21 cited
- → InCl3-Mediated Cascade Reactions for the Construction of Highly Functionalized 1-Oxadecalins(2007)6 cited