Myoglobin-catalyzed intermolecular carbene N–H insertion with arylamine substrates
Chemical Communications2014Vol. 51(8), pp. 1532–1534
Citations Over TimeTop 10% of 2014 papers
Abstract
Engineered variants of the heme-containing protein myoglobin can efficiently catalyze the insertion of α-diazo esters into the N-H bond of arylamines, featuring a combination of high chemoselectivity, elevated turnover numbers, and broad substrate scope.
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