A multiple gadolinium complex decorated fullerene as a highly sensitive T1 contrast agent
Chemical Communications2015Vol. 51(21), pp. 4390–4393
Citations Over TimeTop 10% of 2015 papers
Lirong Wang, Xianglong Zhu, Xingyan Tang, Changqiang Wu, Zijian Zhou, Chengjie Sun, Shun‐Liu Deng, Hua Ai, Jinhao Gao
Abstract
We report a simple strategy to construct a multiple gadolinium complex decorated fullerene (CGDn) as an enhanced T1 contrast agent. The CGDn exhibits much higher T1 relaxivity (∼49.7 mM(-1) s(-1)) than individual Gd-DOTA, and shows excellent T1 contrast enhancement ability both in vitro and in vivo.
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