Rapid formation of a stable boron–nitrogen heterocycle in dilute, neutral aqueous solution for bioorthogonal coupling reactions
Chemical Communications2015Vol. 51(95), pp. 16992–16995
Citations Over TimeTop 10% of 2015 papers
Abstract
Reaction of 2-formylphenylboronic acid with an aromatic hydrazine does not product the expected hydrazone, but rather a boron-containing aromatic heterocycle. The characteristics of the reaction are highly desirable for bioconjugations.
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