Photo-induced coupling reactions of tetrazoles with carboxylic acids in aqueous solution: application in protein labelling
Chemical Communications2016Vol. 52(25), pp. 4702–4705
Citations Over TimeTop 10% of 2016 papers
Abstract
The photo-induced reactions of diaryltetrazoles with carboxylic acids in aqueous solution were investigated. Besides measuring the apparent second-order rate constant and evaluating the functional group compatibility of these reactions, we further incorporated the tetrazoles into SAHA, leading to a new active-site-directed probe for labelling HDACs in both cell lysates and living cells.
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