NIR light/H₂O₂-triggered nanocomposites for a highly efficient and selective synergistic photodynamic and photothermal therapy against hypoxic tumor cells

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Abstract

In this work, smart near-infrared (NIR) light/H2O2-triggered and O2-evolving nanocomposites were designed and applied for efficient production of (1)O2 by converting a deeply penetrating NIR light into a visible light to excite the photosensitizers and achieve a self-sufficiency of the O2 generation in the photodynamic therapy process to overcome the hypoxia-induced drug resistance.

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