Ruthenium nitrosyl functionalized graphene quantum dots as an efficient nanoplatform for NIR-light-controlled and mitochondria-targeted delivery of nitric oxide combined with photothermal therapy
Chemical Communications2017Vol. 53(22), pp. 3253–3256
Citations Over TimeTop 10% of 2017 papers
Min Guo, Huijing Xiang, Yi Wang, Qianling Zhang, Lu An, Shiping Yang, Yinchu Ma, Yucai Wang, Jin‐Gang Liu
Abstract
A mitochondria-targeting nanoplatform for near-infrared-light-controlled release of nitric oxide accompanied by photothermal therapy was developed, which consists of ruthenium nitrosyl functionalized N-doped graphene quantum dots and a triphenylphosphonium moiety. The nanoplatform demonstrated both in vitro and in vivo anti-tumor efficacy upon irradiation with 808 nm light.
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