Synthesis of functionalized pyrroloindolinesviaa visible-light-induced radical cascade reaction: rapid synthesis of (±)-flustraminol B
Chemical Communications2018Vol. 54(54), pp. 7443–7446
Citations Over TimeTop 10% of 2018 papers
Abstract
The development of visible-light-induced synthesis of functionalized pyrroloindolines via a radical cascade reaction is reported. The reaction shows a broad substrate scope and highlights the mild nature of the reaction conditions. A range of substitutions on indole aromatic rings and N-centers is well tolerated, including a free allylic alcohol. Relying on the strategy, a rapid synthesis of (±)-flustraminol B was achieved.
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