The anti-aging mechanism of ginsenosides with medicine and food homology
Citations Over TimeTop 10% of 2023 papers
Abstract
With the acceleration of global aging and the rise in living standards, the achievement of healthy aging is becoming an imperative issue globally. Ginseng, a medicinal plant that has a long history of dietary intake and remarkable medicinal value, has become a research hotspot in the field of food and medicine. Ginsenosides, especially protopanaxadiol-type saponins and protopanaxatriol-type saponins, are among the most important active ingredients in ginseng. Ginsenosides have been found to exhibit powerful and diverse pharmacological activities, such as antiaging, antitumor, antifatigue and immunity enhancement activities. Their effects in antiaging mainly include (1) promotion of metabolism and stem cell proliferation, (2) protection of skin and nerves, (3) modulation of intestinal flora, (4) maintenance of mitochondrial function, and (5) enhancement of telomerase activity. The underlying mechanisms are primarily associated with the intervention of the signaling pathways in apoptosis, inflammation and oxidative stress. In this review, the mechanism of action of ginsenosides in antiaging as well as the potential values of developing ginsenoside-based functional foods and antiaging drugs are discussed.
Related Papers
- → Advances in Saponin Diversity of Panax ginseng(2020)119 cited
- → Ginsenoside profiles and related gene expression during foliation in Panax ginseng Meyer(2014)109 cited
- → Different chilling stresses stimulated the accumulation of different types of ginsenosides in Panax ginseng cells(2016)24 cited
- → Effects of Different Culture Times Genes Expression on Ginsenoside Biosynthesis of the Ginseng Adventitious Roots in Panax ginseng(2023)5 cited
- 인삼의 품질과 약리활성 물질과의 상관성 ( Relationship of Saponin and Non-saponin for the Quality of Ginseng )(1998)