A near-infrared fluorescent probe for imaging peroxynitrite levels in paw edema mice and drug evaluation
Chemical Communications2024Vol. 60(52), pp. 6675–6678
Citations Over TimeTop 17% of 2024 papers
Ling Hu, Sisi Chen, Hui Zhang, Jing‐Jing Chao, Zhen-Zhen Peng, Guojiang Mao, Liufang Hu, Juan Ouyang, Anjie Min, Chunyan Li
Abstract
A near-infrared fluorescent probe (TX-P) for detecting peroxynitrite is constructed. The probe has a near-infrared emission (725 nm), large Stokes shift (125 nm) and excellent sensitivity and selectivity. In addition, TX-P can be used to visualize ONOO- in living cells, image ONOO- in paw edema mice and evaluate anti-inflammatory drugs.
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