A J-aggregating cyanine-based NIR-II optical sensor for DNA aptamer-mediated detection and imaging of quinine
Chemical Communications2025Vol. 61(74), pp. 14117–14120
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Abstract
We report a dye-displacement assay for quinine detection integrating a DNA aptamer with a J-aggregating NIR-II cyanine dye. This platform achieves sensitive, selective, and label-free NIR-II colorimetric and fluorescence sensing, with a fluorescence-based detection limit as low as 0.014 μM in urine solution, and enables NIR-II fluorescence imaging.