Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis
New England Journal of Medicine2001Vol. 345(6), pp. 408–416
Citations Over TimeTop 1% of 2001 papers
Saul N. Faust, Michael Levin, Odile B. Harrison, Robert Goldin, Marion S. Lockhart, Sheila Kondaveeti, Zoltán Lászik, Charles T. Esmon, Robert S. Heyderman
Abstract
In severe meningococcal sepsis, protein C activation is impaired, a finding consistent with down-regulation of the endothelial thrombomodulin-endothelial protein C receptor pathway.
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