Effect of Early versus Deferred Antiretroviral Therapy for HIV on Survival
New England Journal of Medicine2009Vol. 360(18), pp. 1815–1826
Citations Over TimeTop 1% of 2009 papers
Mari M. Kitahata, Stephen J. Gange, Alison G. Abraham, Barry Merriman, Michael S Saag, Amy C. Justice, Robert S. Hogg, Steven G. Deeks, Joseph J. Eron, John T. Brooks, Sean B. Rourke, M. John Gill, Ronald J. Bosch, Jeffrey N. Martin, Marina B. Klein, Lisa P. Jacobson, Benigno Rodríguez, Timothy R. Sterling, Gregory D. Kirk, Sonia Napravnik, Anita Rachlis, Liviana Calzavara, Michael A. Horberg, Michael J. Silverberg, Kelly A. Gebo, James J. Goedert, Constance A. Benson, Ann C. Collier, Stephen E. Van Rompaey, Heidi M. Crane, Rosemary G. McKaig, Bryan Lau, Aimee Freeman, Richard D. Moore
Abstract
The early initiation of antiretroviral therapy before the CD4+ count fell below two prespecified thresholds significantly improved survival, as compared with deferred therapy.
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