FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
New England Journal of Medicine2015Vol. 373(10), pp. 895–907
Citations Over TimeTop 1% of 2015 papers
Melina Claussnitzer, Simon N. Dankel, Kyoung-Han Kim, Gerald Quon, Wouter Meuleman, Christine E. Haugen, Viktoria Glunk, Isabel Sousa, Jacqueline L. Beaudry, Vijitha Puviindran, Nezar Abdennur, Jannel Liu, Per‐Arne Svensson, Yi-Hsiang Hsu, Daniel J. Drucker, Gunnar Mellgren, Chi-chung Hui, Hans Hauner, Manolis Kellis
Abstract
Our results point to a pathway for adipocyte thermogenesis regulation involving ARID5B, rs1421085, IRX3, and IRX5, which, when manipulated, had pronounced pro-obesity and anti-obesity effects. (Funded by the German Research Center for Environmental Health and others.).
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