A Bronchial Genomic Classifier for the Diagnostic Evaluation of Lung Cancer
New England Journal of Medicine2015Vol. 373(3), pp. 243–251
Citations Over TimeTop 1% of 2015 papers
Gerard A. Silvestri, Anil Vachani, Duncan Whitney, Michael Elashoff, Kate Smith, J. Scott Ferguson, E. Parsons, Nandita Mitra, Jerome S. Brody, Marc E. Lenburg, Avrum Spira
Abstract
The gene-expression classifier improved the diagnostic performance of bronchoscopy for the detection of lung cancer. In intermediate-risk patients with a nondiagnostic bronchoscopic examination, a negative classifier score provides support for a more conservative diagnostic approach. (Funded by Allegro Diagnostics and others; AEGIS-1 and AEGIS-2 ClinicalTrials.gov numbers, NCT01309087 and NCT00746759.).
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