Randomized Trial of Stent versus Surgery for Asymptomatic Carotid Stenosis
New England Journal of Medicine2016Vol. 374(11), pp. 1011–1020
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Kenneth Rosenfield, Jon S. Matsumura, Seemant Chaturvedi, Tom Riles, Gary M. Ansel, D. Chris Metzger, Lawrence R. Wechsler, Michael R. Jaff, William A. Gray
Abstract
In this trial involving asymptomatic patients with severe carotid stenosis who were not at high risk for surgical complications, stenting was noninferior to endarterectomy with regard to the rate of the primary composite end point at 1 year. In analyses that included up to 5 years of follow-up, there were no significant differences between the study groups in the rates of non-procedure-related stroke, all stroke, and survival. (Funded by Abbott Vascular; ACT I ClinicalTrials.gov number, NCT00106938.).
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