A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest
New England Journal of Medicine2018Vol. 379(8), pp. 711–721
Citations Over TimeTop 1% of 2018 papers
Gavin D. Perkins, Chen Ji, Charles D. Deakin, Tom Quinn, Jerry P. Nolan, Charlotte Scomparin, Scott Regan, John Long, Anne‐Marie Slowther, Helen Pocock, John J. Black, Fionna Moore, Rachael Fothergill, Nigel Rees, Lyndsey O’Shea, Mark Docherty, Imogen Gunson, Kyee Han, Karl Charlton, Judith Finn, Stavros Petrou, Nigel Stallard, Simon Gates, Ranjit Lall
Abstract
In adults with out-of-hospital cardiac arrest, the use of epinephrine resulted in a significantly higher rate of 30-day survival than the use of placebo, but there was no significant between-group difference in the rate of a favorable neurologic outcome because more survivors had severe neurologic impairment in the epinephrine group. (Funded by the U.K. National Institute for Health Research and others; Current Controlled Trials number, ISRCTN73485024 .).
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