Antimicrobial Susceptibility and Frequency of Occurrence of Clinical Blood Isolates in Europe from the SENTRY Antimicrobial Surveillance Program, 1997 and 1998

Citations Over TimeTop 1% of 2000 papers

Abstract

As part of the European arm of the SENTRY Antimicrobial Surveillance Program, 25 European university hospitals referred 9613 blood isolates for in vitro testing against >20 antimicrobial agents. Escherichia coli, Staphylococcus aureus, coagulase-negative Staphylococcus, Pseudomonas aeruginosa, and Klebsiella pneumoniae were the 5 most frequent isolates and accounted for two-thirds of all referrals, with minor regional variation. Of these, approximately 0.36% of E. coli and 16.7% of K. pneumoniae isolates proved to be potential extended-spectrum beta-lactamase producers, and their incidence clearly varied regionally. Quinolone resistance was detected among gram-negative species; in particular, P. aeruginosa and Acinetobacter species. Considerable regional variation was observed in the incidences of methicillin resistance in S. aureus and penicillin resistance in Streptococcus pneumoniae. The incidence of vancomycin resistance in enterococci was relatively low overall and primarily associated with Enterococcus faecium. However, extrapolation of these data to smaller and nonteaching hospitals should be undertaken with caution, since resistance rates may be lower in these facilities.

Related Papers

• → A PCR assay for identification of Enterococcus faecium(1997)125 cited
• → Emergence of linezolid-resistant Enterococcus faecium during treatment of enterococcal infections(2003)24 cited
• Establishment of a Duplex PCR Assay for Simultaneous Detection of Sheep-originated Enterococcus and Enterococcus faecium(2015)
• Establishment of Rapid and Simple Primary Screening of Enterococcus(2010)
• → Rapid molecular identification of fecal origin-colonies growing on Enterococcus spp.-specific culture methods(2016)