Characterization of the Relationship between Polysaccharide Intercellular Adhesin and Hemagglutination inStaphylococcus epidermidis
The Journal of Infectious Diseases1999Vol. 179(6), pp. 1561–1564
Citations Over TimeTop 10% of 1999 papers
Abstract
To determine whether a relationship exists between biofilm formation and hemagglutination in Staphylococcus epidermidis, 20 skin isolates and 19 prosthetic valve endocarditis isolates were characterized for biofilm formation, hemagglutination, and the presence of a 357-bp polymerase chain reaction product within icaA. A strong association existed between biofilm formation, which has been linked to strains that produce polysaccharide intercellular adhesin (PIA), and hemagglutination. Strains that produced biofilm were significantly (P/=1/128). It was concluded that production of PIA and hemagglutination are strongly associated and that PIA, at least in part, mediates hemagglutination in S. epidermidis.
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