Linezolid-Associated Toxic Optic Neuropathy: A Report of 2 Cases
Clinical Infectious Diseases2003Vol. 37(10), pp. 1389–1391
Citations Over TimeTop 1% of 2003 papers
Abstract
We describe 2 cases in which the prolonged use of linezolid to treat complicated methicillin-resistant Staphylococcus aureus infections was followed by acutely developed blurred vision and progressive loss of vision and color perception during the ensuing few weeks. Both patients received a diagnosis of toxic optic neuropathy, and linezolid therapy was stopped. The patients experienced an initial rapid partial improvement and a subsequent gradual, almost complete, recovery over many months.
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