Optimal Testing Parameters for Blood Cultures
Citations Over TimeTop 10% of 2004 papers
Abstract
The effects of volume of blood, number of consecutive cultures, and incubation time on pathogen recovery were evaluated for 37,568 blood cultures tested with the automated BACTEC 9240 instrument (Becton Dickinson Diagnostic Instrument Systems) at a tertiary care center over the period of 12 June 1996 through 12 October 1997. When the results for this study were compared with previous data published for manual broth-based blood culture systems and patient samples obtained in the 1970s and 1980s, the following were found: (1) the percentage increase in pathogen recovery per milliliter of blood is less, (2) more consecutive blood culture sets over a 24-h period are required to detect bloodstream pathogens, and (3) a shorter duration of incubation is required to diagnose bloodstream infections. Guidelines developed in the 1970s and 1980s for processing and culturing blood may require revision.
Related Papers
- → Repeating blood cultures in neutropenic children with persistent fevers when the initial blood culture is negative(2012)31 cited
- → Antimicrobial Therapy of Septicemic Patients in Intensive Care Units before and after Blood Culture Reporting(1991)24 cited
- → Comparison of PCR and conventional blood culture to analyze blood from dogs with suspected sepsis(2013)7 cited
- Continuous Detection of Procalcitonin and Blood Culture in the United Diagnosis of Bacteremia(2011)
- [A year of blood cultures at the Associated Hospitals of Trieste: a critical evaluation of the clinico-laboratory approach to the patient with suspected bacteremia].(1985)