Three Cases of Q Fever Osteomyelitis in Children and a Review of the Literature
Clinical Infectious Diseases2004Vol. 39(7), pp. e61–e66
Citations Over TimeTop 20% of 2004 papers
Clare Nourse, Anthony Allworth, Andrew Jones, Robert Horvath, Joe McCormack, Jeremy A. Bartlett, D. Neil Hayes, Jennifer Robson
Abstract
Q fever is a common zoonosis worldwide. Awareness of the disease and newer diagnostic modalities have resulted in increasing recognition of unusual manifestations. We report 3 cases of Q fever osteomyelitis in children and review the literature on 11 other reported cases. The cases demonstrate that Coxiella burnetii can cause granulomatous osteomyelitis that presents without systemic symptoms and frequently results in a chronic, relapsing, multifocal clinical course. Optimal selection and duration of antimicrobial therapy and methods of monitoring therapy are currently uncertain.
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