Hemochromatosis Mutations in Iranians with Hepatitis B Virus Infection
Clinical Infectious Diseases2005Vol. 40(3), pp. e19–e21
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Hossein Sendi, Tahereh Ghaziani, Mohammad Reza Zali, Peyman Adibi, Mahvash Agah, Maryam Jazayeri, Saeid Shahraz, Lars O. Magnius, Herbert L. Bonkovsky
Abstract
In this study, the frequencies of the common hemochromatosis gene mutations were assessed in 75 Iranian subjects with chronic hepatitis B infection. We found that the major C282Y mutation was significantly more frequent in subjects infected with hepatitis B virus (4%) than in 194 control subjects (0%, P=.02; Fisher's exact test).
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