The Role of Immune Reconstitution Inflammatory Syndrome in AIDS‐RelatedCryptococcus neoformansDisease in the Era of Highly Active Antiretroviral Therapy
Clinical Infectious Diseases2005Vol. 40(7), pp. 1049–1052
Citations Over TimeTop 1% of 2005 papers
Samuel A. Shelburne, Jorge Darcourt, A. Clinton White, Stephen B. Greenberg, Richard J. Hamill, Robert L. Atmar, Fehmida Visnegarwala
Abstract
This study of human immunodeficiency virus (HIV)-infected patients coinfected with Cryptococcus neoformans found that 30% of patients who initiated highly active antiretroviral therapy developed immune reconstitution inflammatory syndrome (IRIS). Patients with C. neoformans-related IRIS had higher cerebrospinal fluid opening pressures, glucose levels, and white blood cell counts, compared with patients with typical HIV-associated C. neoformans meningitis.
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