Association between Acquired Rifamycin Resistance and the Pharmacokinetics of Rifabutin and Isoniazid among Patients with HIV and Tuberculosis
Clinical Infectious Diseases2005Vol. 40(10), pp. 1481–1491
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Marc Weiner, Debra Benator, W. J. Burman, Charles A. Peloquin, Abdul Qadir Khan, Andrew Vernon, Brenda Jones, Claudia Silva‐Trigo, Zhen Zhao, Thomas Hodge
Abstract
Lower plasma concentrations of rifabutin and, perhaps, isoniazid were associated with ARR failure or relapse in patients with tuberculosis and HIV infection treated with twice-weekly therapy.
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