Respiratory Syncytial Virus–Specific CD8+Memory T Cell Responses in Elderly Persons
The Journal of Infectious Diseases2005Vol. 191(10), pp. 1710–1718
Citations Over TimeTop 10% of 2005 papers
Godelieve J. de Bree, Jojanneke Heidema, Ester M. M. van Leeuwen, Grada M. van Bleek, René E. Jonkers, Henk M. Jansen, René A. W. van Lier, Theo A. Out
Abstract
We provide evidence that a pool of functional RSV-specific CD8(+) memory T cells persists in the peripheral blood of healthy individuals and patients with COPD. Low numbers of RSV-specific memory T cells in the elderly and in patients with COPD may explain the increased susceptibility to RSV infection in these populations.
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