Linezolid-Induced Inhibition of Mitochondrial Protein Synthesis
Clinical Infectious Diseases2006Vol. 42(8), pp. 1111–1117
Citations Over TimeTop 10% of 2006 papers
An S. De Vriese, Rudy Van Coster, Joél Smet, Sara Seneca, A. M. Lovering, Lindsey Van Haute, Ludo Vanopdenbosch, Jean‐Jacques Martin, Chantal Ceuterick‐de Groote, Stefaan J. Vandecasteele, Johan R. Boelaert
Abstract
These results provide direct evidence that linezolid inhibits mitochondrial protein synthesis with potentially severe clinical consequences. Prolonged courses of linezolid should be avoided if alternative treatment options are available.
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