The US Capitol Bioterrorism Anthrax Exposures: Clinical Epidemiological and Immunological Characteristics
The Journal of Infectious Diseases2006Vol. 195(2), pp. 174–184
Citations Over TimeTop 25% of 2006 papers
Denise L. Doolan, Daniel Freilich, Gary T. Brice, Timothy Burgess, Mara P. Berzins, Robert L. Bull, Norma L. Graber, Jason Dabbs, Lori Shatney, David L. Blazes, Lolita Bebris, Maria F. Malone, John F. Eisold, Alfred Mateczun, Gregory Martin
Abstract
Anthrax spores primed cellular and possibly antibody immune responses in a dose-dependent manner and may have enhanced vaccine boost and recall responses. Immune responses were detected inside the perimeter and outside the exposure zone, which implies more-extensive spore exposure than was predicted. Despite postexposure prophylaxis with antibiotics, inhalation of B. anthracis spores resulted in stimulation of the immune system and possibly subclinical infection, and the greater the exposure, the more complete the immune response. The significance of low-level exposure should not be underestimated.
Related Papers
- → Detection of Anthrax Toxin in the Serum of Animals Infected with Bacillus anthracis by Using Engineered Immunoassays(2006)124 cited
- → The early humoral immune response toBacillus anthracistoxins in patients infected with cutaneous anthrax(2011)29 cited
- → Quantitative Determination of Lethal Toxin Proteins in Culture Supernatant of Human Live Anthrax Vaccine Bacillus anthracis A16R(2016)14 cited
- → Study of Immunization against Anthrax with the Purified Recombinant Protective Antigen of Bacillus anthracis(1998)46 cited
- Progress in research on neutralizing antibody against Bacillus anthracis(2010)