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Ebola Hemorrhagic Fever and Pregnancy

The Journal of Infectious Diseases1999Vol. 179(s1), pp. S11–S12

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Kibadi Mupapa, Woliere Mukundu, Mpia Ado Bwaka, M. Kipasa, Ann De Roo, Kivudi Kuvula, Kapay Kibadi, Matondo Massamba, Djuma Ndaberey, Robert Colebunders, J. J. Muyembe‐Tamfum

Abstract

Fifteen (14%) of 105 women with Ebola hemorrhagic fever hospitalized in the isolation unit of the Kikwit General Hospital (Democratic Republic of the Congo) were pregnant. In 10 women (66%) the pregnancy ended with an abortion. In 3 of them, a curettage was performed, and all 3 received a blood transfusion from an apparently healthy person. One woman was prematurely delivered of a stillbirth. Four pregnant women died during the third trimester of their pregnancy. All women presented with severe bleeding. Only 1 survived; she had a curettage because of an incomplete abortion after 8 months of amenorrhea. The mortality among pregnant women with Ebola hemorrhagic fever (95.5%) was slightly but not significantly higher than the overall mortality observed during the Ebola epidemic in Kikwit (77%; 245/316 infected persons).

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