Direct In Vivo Assessment of Microcirculatory Dysfunction in Severe Falciparum Malaria
The Journal of Infectious Diseases2007Vol. 197(1), pp. 79–84
Citations Over TimeTop 1% of 2007 papers
Arjen M. Dondorp, Can İnce, Prakaykaew Charunwatthana, Josh Hanson, Anne-Marije van Kuijen, M A Faiz, Md. Rezaur Rahman, M. Hasan, E. Bin Yunus, Aniruddha Ghose, Ronnatrai Ruangveerayut, Direk Limmathurotsakul, Keshen R. Mathura, Nicholas J. White, Nicholas Day
Abstract
Patients with severe falciparum malaria show extensive microvascular obstruction that is proportional to the severity of the disease. This finding underscores the prominent role that microvascular obstruction plays in the pathophysiology of severe malaria and illustrates the fundamental difference between the microvascular pathophysiology of malaria and that of bacterial sepsis.
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