High Sensitivity of Human Leukocyte Antigen–B*5701 as a Marker for Immunologically Confirmed Abacavir Hypersensitivity in White and Black Patients
Clinical Infectious Diseases2008Vol. 46(7), pp. 1111–1118
Citations Over TimeTop 1% of 2008 papers
Michael S. Saag, Rukmini Balu, Elizabeth J. Phillips, Philip S. Brachman, Claudia Martorell, William J. Burman, Britt Stancil, Michael Mosteller, Cindy Brothers, Paul Wannamaker, Arlene R. Hughes, Denise Sutherland‐Phillips, S. Mallal, Mark S. Shaefer, Study of Hypersensitivity to Abacavir and Pharmacogenetic Evaluation Study Team
Abstract
Although IC ABC HSRs are uncommon in black persons, the 100% sensitivity of HLA-B*5701 as a marker for IC ABC HSRs in both US white and black patients suggests similar implications of the association between HLA-B*5701 positivity and risk of ABC HSRs in both races.
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