Human Parechoviruses as an Important Viral Cause of Sepsislike Illness and Meningitis in Young Children
Clinical Infectious Diseases2008Vol. 47(3), pp. 358–363
Citations Over TimeTop 10% of 2008 papers
Katja C. Wolthers, Kimberley Benschop, Janke Schinkel, Richard Molenkamp, Rosemarijn M. Bergevoet, Ingrid J. B. Spijkerman, H. Carlijn Kraakman, Dasja Pajkrt
Abstract
EV-specific PCRs do not detect HPeVs. The addition of an HPeV-specific PCR has led to a 31% increase in detection of a viral cause of neonatal sepsis or central nervous system symptoms in children aged <5 years. HPeV can be considered to be the second cause of viral sepsis and meningitis in young children, and rapid identification of HPeV by PCR could contribute to shorter duration of both antibiotic use and hospital stay.
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