Low Serum Mannose‐Binding Lectin Level Increases the Risk of Death due to Pneumococcal Infection
Clinical Infectious Diseases2008Vol. 47(4), pp. 510–516
Citations Over TimeTop 10% of 2008 papers
Damon P. Eisen, Melinda M. Dean, Marja A. Boermeester, Katy Fidler, Anthony Gordon, Gitte Kronborg, Jürgen F. J. Kun, YL Lau, Antoni Payeras, Helgi Valdimarsson, Stephen J. Brett, Wai‐Ki Ip, Joan Milà, Mark Peters, Saedís Saevarsdóttir, J. W. Oliver van Till, Charles Hinds, Emma S. McBryde
Abstract
We defined a serum level for MBL deficiency that can be used with confidence in future studies of MBL disease associations. The risk of death was increased among MBL-deficient patients with severe pneumococcal infection, highlighting the pathogenic significance of this innate immune defence protein.
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