Herpes Simplex Encephalitis during Treatment with Tumor Necrosis Factor–α Inhibitors
Clinical Infectious Diseases2009Vol. 49(6), pp. 924–927
Citations Over TimeTop 10% of 2009 papers
Russell D. Bradford, April C. Pettit, Patty W. Wright, Mark J. Mulligan, Larry W. Moreland, David McLain, John W. Gnann, Karen C. Bloch
Abstract
We report 3 cases of herpes simplex virus encephalitis in patients receiving tumor necrosis factor-alpha (TNF-alpha) inhibitors for rheumatologic disorders. Although TNF-alpha inhibitors have been reported to increase the risk of other infectious diseases, to our knowledge, an association between anti-TNF-alpha drugs and herpes simplex virus encephalitis has not been previously described.
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