Campylobacter jejuniStrain CG8421: A Refined Model for the Study of Campylobacteriosis and Evaluation ofCampylobacterVaccines in Human Subjects
Clinical Infectious Diseases2009Vol. 49(10), pp. 1512–1519
Citations Over TimeTop 10% of 2009 papers
David R. Tribble, Shahida Baqar, Marya P. Carmolli, Chad K. Porter, Kristen K. Pierce, Katrin S. Sadigh, Patricia Guerry, Catherine J. Larsson, David Rockabrand, Cassandra H. Ventone, Frédéric Poly, Caroline E. Lyon, Sandra Dakdouk, A. Fingar, Theron Gilliland, Patrick Daunais, Erika Jones, Stacia Rymarchyk, Christopher D. Huston, Michael J. Darsley, Beth D. Kirkpatrick
Abstract
The C. jejuni CG8421 challenge model provides a safe and effective tool, without the risk of Guillain-Barré syndrome. The model demonstrates high attack rates after lower doses of challenge inoculum, provides further understanding of immunologic responses, and permits future investigation of candidate Campylobacter vaccines.
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