An Outbreak of Burkholderia cepacia Lower Respiratory Tract Infection Associated With Contaminated Albuterol Nebulization Solution
Citations Over TimeTop 25% of 1996 papers
Abstract
An outbreak of Burkholderia cepacia lower respiratory tract colonization and infection occurred in the adult intensive-care units in various geographic locations throughout our hospital. Forty-four patients became colonized or infected over an 11-month period, whereas B cepacia had been isolated from only 13 patients in the preceding 48 months. Environmental cultures revealed the source to be extrinsically contaminated albuterol nebulization solution. Polymerase chain reaction-ribotyping confirmed the genetic relatedness of the B cepacia patient isolates and the contaminated albuterol. After extensive infection control training for the respiratory therapy staff, including attention to nebulization technique, washing and drying the nebulizer cup, and good handwashing, there have not been any new cases.
Related Papers
- → Respiratory Infections, Acute(2016)16 cited
- → Therapeutic considerations: Lower respiratory tract infections in smokers(1992)7 cited
- Analysis on Indexes of Immune Function in Children with Respiratory Tract Infection(2011)
- → Respiratory Infections, Acute(2008)
- → A study to assess the prevalence of respiratory tract infections among under-five children in Chemudugunta Village at Nellore, A.P(2019)