Delayed Clearance of Viral Load and Marked Cytokine Activation in Severe Cases of Pandemic H1N1 2009 Influenza Virus Infection
Clinical Infectious Diseases2010Vol. 50(6), pp. 850–859
Citations Over TimeTop 1% of 2010 papers
Kelvin Kai‐Wang To, Ivan Fan‐Ngai Hung, Iris W. S. Li, Kar‐Lung Lee, Chi‐Kwan Koo, Wing‐Wa Yan, Raymond W. Liu, Ka‐Ying Ho, Kwok‐Hong Chu, Chi‐Leung Watt, Wei‐Kwang Luk, Kang‐Yiu Lai, Fu‐Loi Chow, Thomas Mok, Tom Buckley, Jasper Fuk‐Woo Chan, Samson S. Y. Wong, Bo‐Jian Zheng, Honglin Chen, Candy C. Y. Lau, Herman Tse, Vincent Chi‐Chung Cheng, Kwok‐Hung Chan, Kwok‐Yung Yuen
Abstract
The slower control of viral load and immunodysregulation in severe cases mandate the search for more effective antiviral and immunomodulatory regimens to stop the excessive cytokine activation resulting in ARDS and death.
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