Neural Correlates of Antidepressant Treatment Response in Adolescents with Major Depressive Disorder
Journal of Child and Adolescent Psychopharmacology2016Vol. 26(8), pp. 705–712
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Kathryn R. Cullen, Bonnie Klimes‐Dougan, Dung Pham Vu, Mindy Westlund Schreiner, Bryon A. Mueller, Lynn E. Eberly, Jazmin Camchong, Ana Westervelt, Kelvin O. Lim
Abstract
The findings represent a foothold for advancing understanding of pathophysiology of MDD in adolescents by revealing the critical neural circuitry changes that underlie a positive response to a standard treatment. Although preliminary, the present study provides a research platform for future work needed to confirm these biomarkers at a larger scale before using them in future target engagement studies of novel treatments.
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