Does Recombinant Human Thyrotropin-Stimulated Positron Emission Tomography with [18F]Fluoro-2-Deoxy- d -Glucose Improve Detection of Recurrence of Well-Differentiated Thyroid Carcinoma in Patients with Low Serum Thyroglobulin?
Thyroid2009Vol. 20(1), pp. 15–23
Citations Over TimeTop 14% of 2009 papers
Pierre Véra, Caroline Kuhn-Lansoy, Agathe Edet‐Sanson, Sébastien Hapdey, Romain Modzelewski, Anne Hitzel, Joëlle d'Anjou, Jean-Pierre Basuyau
Abstract
In the diagnosis of recurrent disease in patients with differentiated thyroid carcinoma and low Tg level, the sensitivity of rhTSH-stimulated PET/CT-FDG seems to be low and no correlation was observed between PET/CT-FDG findings and Tg level. However, positive PET-FDG results have been found in 9/44 (20%) patients with serum Tg levels lower than 10 microg/L. Therefore, this series shows that a cutoff value of 10 microg/L for the Tg under T(4) is probably not the best criteria to select patient candidates for PET/CT-FDG examination to detect the recurrence of differentiated thyroid carcinoma.
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