Leptin Administration Restores the Fasting-Induced Increase of Hepatic Type 3 Deiodinase Expression in Mice
Thyroid2011Vol. 22(2), pp. 192–199
Citations Over TimeTop 23% of 2011 papers
Anita Boelen, Mieke van Beeren, Xander G. Vos, Olga V. Surovtseva, Evita Belegri, Dirk‐Jan Saaltink, Erno Vreugdenhil, Andries Kalsbeek, Joan Kwakkel, Eric Fliers
Abstract
Leptin administration selectively restores starvation-induced increased hepatic D3 expression independently of serum thyroid hormone concentrations. The present study shows that fasting-induced changes in mRNA expression of genes involved in hepatic hormone metabolism are influenced not only by decreased serum thyroid hormone levels but also by serum leptin.
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