MiR-20b Displays Tumor-Suppressor Functions in Papillary Thyroid Carcinoma by Regulating the MAPK/ERK Signaling Pathway
Thyroid2016Vol. 26(12), pp. 1733–1743
Citations Over TimeTop 10% of 2016 papers
Shubin Hong, Shuang Yu, Jin Li, Yali Yin, Yujie Liu, Quan Zhang, Hongyu Guan, Yanbing Li, Haipeng Xiao
Abstract
These results indicate for the first time that miR-20b displays tumor-suppressor functions in PTC. By targeting SOS1 and ERK2, miR-20b inhibits the activity of the MAPK/ERK signaling pathway. The findings suggest that miR-20b may play an important role in PTC initiation, progression, and metastasis, and may provide a potential therapeutic target for PTC.
Related Papers
- → Antioxidant-Rich Extracts of Terminalia ferdinandiana Interfere with Estimation of Cell Viability(2019)32 cited
- → Characterization and comparison of acridine orange/propidium iodide and acridine/DAPI viability detection methods for cell and gene therapy development(2023)3 cited
- → Fruitlessis in the Regulatory Pathway by Which EctopicMini-WhiteandTransformerInduce Bisexual Courtship inDrosophila(2000)21 cited
- DMP1's signal pathway via MAPK-ERK(2013)
- 探討與MAPK/ERK訊息傳遞相關之新穎微型RNA在訊息傳遞之調控及對黑色素瘤的作用;Exploration of Novel MAPK/ERK Related Micrornas in Regulation of MAPK/ERK Signaling Pathway and Their Functional Effects in Melanoma(2016)