Data mining using the Catalogue of Somatic Mutations in Cancer BioMart
Database2011Vol. 2011(0), pp. bar018–bar018
Citations Over TimeTop 10% of 2011 papers
Rebecca Shepherd, Simon Forbes, David Beare, Sally Bamford, Charlotte G. Cole, S. Ward, Nidhi Bindal, Paramasamy Gunasekaran, Mingming Jia, Chai Yin Kok, Kwong‐Sak Leung, Andrew Menzies, Adam P. Butler, Jon W. Teague, Peter J. Campbell, Michael R. Stratton, PA Futreal
Abstract
Catalogue of Somatic Mutations in Cancer (COSMIC) (http://www.sanger.ac.uk/cosmic) is a publicly available resource providing information on somatic mutations implicated in human cancer. Release v51 (January 2011) includes data from just over 19,000 genes, 161,787 coding mutations and 5573 gene fusions, described in more than 577,000 tumour samples. COSMICMart (COSMIC BioMart) provides a flexible way to mine these data and combine somatic mutations with other biological relevant data sets. This article describes the data available in COSMIC along with examples of how to successfully mine and integrate data sets using COSMICMart. DATABASE URL: http://www.sanger.ac.uk/genetics/CGP/cosmic/biomart/martview/.
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