Identification of the novel class D β-lactamase OXA-679 involved in carbapenem resistance in Acinetobacter calcoaceticus
Journal of Antimicrobial Chemotherapy2019Vol. 74(6), pp. 1494–1502
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Manuela Tietgen, Jan S. Kramer, Steffen Brunst, Bardya Djahanschiri, Sonali Wohra, Paul G. Higgins, Marko Weidensdorfer, Sara Riedel-Christ, Klaas M. Pos, Aitor Gonzaga, Matthias Steglich, Ulrich Nübel, Ingo Ebersberger, Ewgenij Proschak, Stephan Göttig
Abstract
We identified blaOXA-679 in a clinical A. calcoaceticus isolate that represents a member of the new OXA-679 family and that conferred high-level carbapenem resistance in vitro and in vivo.
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