Predictors for the development of microalbuminuria and interaction with renal function
Journal of Hypertension2017Vol. 35(12), pp. 2501–2509
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Christos Chatzikyrkou, Jan Menne, Joseph L. Izzo, Giancarlo Viberti, Ton J. Rabelink, Luís M. Ruilope, Christian Rump, Peter R. Mertens, Hermann Haller
Abstract
Predictors of new onset microalbuminuria are the classical cardiovascular risk factors. Microalbuminuria development was associated with baseline UACR but not baseline eGFR, whereas eGFR decrease after introduction of olmesartan was dependent on baseline eGFR but not on baseline UACR. The effects of olmesartan on microalbuminuria development and on eGFR decrease are probably mediated by different mechanisms.Clinical Trials.gov number, NCT00185159.
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